About Chlorhexidine: History of Chlorhexidine
Chlorhexidine has been in use for almost 60 years and has been used in more than 60 pharmaceuticals and medical devices. Over that period, it has proven its broad-spectrum efficacy and safety. Chlorhexidine, in many instances, has become the standard in patient care for the prevention of disease and nosocomial infection. Although the molecule has been in use for a long time, it is still being used in new applications.
1954 — Chlorhexidine digluconate is first introduced commercially in the United Kingdom as a disinfectant and topical antiseptic.5
2010 — The first chlorhexidine-impregnated needless connectors are cleared by the FDA.
2010 — The first chlorhexidine-impregnanted Peripherally Inserted Central Catheter (PICC) is cleared as an antimicrobial catheter.
1954 — The Imperial Chemical Industries, Limited publishes an article about a new investigational antimicrobial. The article entitled "1:6-Di-4'-Chlorophenyldiguanidohexane ("Hibitane"). Laboratory Investigation of a New Antibacterial Agent of High Potency" explains the promise of chlorhexidine.4
1970s — Chlorhexidine is first introduced into the US.21
1981 — The first urology lubricant with chlorhexidine is cleared by the FDA.
AGB+ is a registered trademark of Teleflex Incorporated or its affiliates.
Toothette, Q•Care and Sage are registered trademarks of Sage Products Incorporated.
BioPatch is a registered trademark of Ethicon Incorporated.
ICI and the Imperial Chemical Industries, Limited are trademarks or registered trademarks of Akzo Nobel N.V.